Titular completo: Un nuevo estudio sugiere que malos tratos a los niños dejan "cicatrices" moleculares en el ADN de los espermatozoides de las víctimas. Los malos tratos a los niños pueden dejar marcas que van incluso más allá del trauma psicológico al grabarse físicamente en el ADN de las personas, según un nuevo estudio de Harvard. La investigación basada en una pequeña muestra de hombres encontró diferencias en las marcas químicas dentro del código genético de aquellos que habían sufrido malos tratos cuando eran niños.
Comentarios
Vaya bulo le han colado al Independent. El DNA no es regrabable en un mismo individuo, que no es un floppy disk...
#1 Dice sugiere, no afirma nada. https://www.nature.com/articles/s41398-018-0252-1 Go to #3
No deja de ser una hipótesis de trabajo y como dicen al final Our results recommend further consideration of this . Artículo: Exposure to childhood abuse is associated with human sperm DNA methylation Translational Psychiatryvolume 8, Article number: 194 (2018) https://www.nature.com/articles/s41398-018-0252-1
Childhood abuse greatly precedes the time period in which the ejaculated sperm were dividing and maturing, thus could not directly affect sperm DNAm at this stage. Instead, childhood exposures may affect the epigenome of spermatogonia, which then gets propagated during spermatogenesis in adulthood35,83. Additionally, our results suggest that childhood abuse may lead to adulthood exposures that affect the sperm epigenome during spermatogenesis23. Regardless of their origin, it is tempting to speculate that these DNAm marks are somehow propagated to the offspring. However, research in human developmental biology has not yet provided strong evidence for this possibility82. Moreover, we note that offspring inherits the material from a single sperm, for which each CpG site is either methylated or unmethylated. If differences in DNAm associated with child abuse render affected sperm less likely to fertilize an egg, then the potential impact of these changes on offspring would likewise be reduced. Studies in humans have documented adverse neurodevelopmental outcomes in offspring of persons exposed to severe psychosocial stressors, in particular, to childhood abuse38,84,85,86,87,88,89,90,91. The hypothesis that the experience of stress may affect offspring through the parental epigenome has been raised as a potential mechanism for these associations92,93. While this possibility is intriguing, molecular evidence from human germ cells remains sparse. Our results recommend further consideration of this promising hypothesis.
Exacto, se la han colado