#4 Un nuevo estudio sugiere que los malos tratos dejan "cicatrices" en el ADN de los espermatozoides (eng)

--590032-- — Thu, 11 Oct 2018 15:19:40 +0000

#1 Dice sugiere, no afirma nada. www.nature.com/articles/s41398-018-0252-1 Go to #3

» autor: --590032--

#3 Un nuevo estudio sugiere que los malos tratos dejan "cicatrices" en el ADN de los espermatozoides (eng)

--590032-- — Thu, 11 Oct 2018 15:10:39 +0000

No deja de ser una hipótesis de trabajo y como dicen al final Our results recommend further consideration of this . Artículo: Exposure to childhood abuse is associated with human sperm DNA methylation Translational Psychiatryvolume 8, Article number: 194 (2018) www.nature.com/articles/s41398-018-0252-1
Childhood abuse greatly precedes the time period in which the ejaculated sperm were dividing and maturing, thus could not directly affect sperm DNAm at this stage. Instead, childhood exposures may affect the epigenome of spermatogonia, which then gets propagated during spermatogenesis in adulthood35,83. Additionally, our results suggest that childhood abuse may lead to adulthood exposures that affect the sperm epigenome during spermatogenesis23. Regardless of their origin, it is tempting to speculate that these DNAm marks are somehow propagated to the offspring. However, research in human developmental biology has not yet provided strong evidence for this possibility82. Moreover, we note that offspring inherits the material from a single sperm, for which each CpG site is either methylated or unmethylated. If differences in DNAm associated with child abuse render affected sperm less likely to fertilize an egg, then the potential impact of these changes on offspring would likewise be reduced. Studies in humans have documented adverse neurodevelopmental outcomes in offspring of persons exposed to severe psychosocial stressors, in particular, to childhood abuse38,84,85,86,87,88,89,90,91. The hypothesis that the experience of stress may affect offspring through the parental epigenome has been raised as a potential mechanism for these associations92,93. While this possibility is intriguing, molecular evidence from human germ cells remains sparse. Our results recommend further consideration of this promising hypothesis.

» autor: --590032--

#2 Un nuevo estudio sugiere que los malos tratos dejan "cicatrices" en el ADN de los espermatozoides (eng)

--35057-- — Thu, 11 Oct 2018 14:51:44 +0000

Exacto, se la han colado

» autor: --35057--

#1 Un nuevo estudio sugiere que los malos tratos dejan "cicatrices" en el ADN de los espermatozoides (eng)

reithor — Thu, 11 Oct 2018 14:46:38 +0000

Vaya bulo le han colado al Independent. El DNA no es regrabable en un mismo individuo, que no es un floppy disk...

» autor: reithor

Menéame: comentarios [3025406]

#4 Un nuevo estudio sugiere que los malos tratos dejan "cicatrices" en el ADN de los espermatozoides (eng)

#3 Un nuevo estudio sugiere que los malos tratos dejan "cicatrices" en el ADN de los espermatozoides (eng)

#2 Un nuevo estudio sugiere que los malos tratos dejan "cicatrices" en el ADN de los espermatozoides (eng)

#1 Un nuevo estudio sugiere que los malos tratos dejan "cicatrices" en el ADN de los espermatozoides (eng)